RT Book, Section A1 Perdomo, Marisa A2 Davenport, Todd E. A2 Kulig, Kornelia A2 Sebelski, Chris A. A2 Gordon, James A2 Watts, Hugh G. SR Print(0) ID 1184026971 T1 Edema T2 Diagnosis for Physical Therapists: A Symptom-Based Approach YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780803615281 LK fadavispt.mhmedical.com/content.aspx?aid=1184026971 RD 2024/04/24 AB This chapter describes pathology that may lead to edema. Edema is enlargement of the soft tissues secondary to excess water accumulation. It can be classified as intracellular or extracellular. Intracellular edema develops when there is direct injury to tissues, causing inflammatory insult to the cell or alterations in cellular metabolism and resulting in an increase in intracellular sodium and water. Extracellular edema is an abnormal accumulation of fluid and protein molecules in the intercellular spaces of tissues.1 Edema that develops in the arms or legs, which is the focus of this chapter, is called peripheral edema. Peripheral edema may be due to either a systemic dysfunction such as cardiac or renal insufficiency or an obstruction such as a blood clot or tumor. The development of edema may be associated with loss of skin mobility, loss of joint range of motion, loss of joint shape and definition, loss of muscle strength, pain, and changes in skin color, texture, and temperature.2