RT Book, Section A1 McCulloch, Joseph M. A2 McCulloch, Joseph M. A2 Kloth, Luther C. SR Print(0) ID 1184831822 T1 Venous Insufficiency and Ulceration T2 Wound Healing Evidence-Based Management, 4e YR 2010 FD 2010 PB McGraw-Hill Education PP New York, NY SN 9780803619043 LK fadavispt.mhmedical.com/content.aspx?aid=1184831822 RD 2024/03/28 AB It has been suggested that approximately 90% of the estimated 600,000 leg ulcers seen annually in the United States are due to chronic venous disease or mixed arteriovenous insufficiency.1 In addition, 5% to 8% of the world's population is affected by venous disease, making this a costly problem from both an economic and quality-of-life perspective.2,3,4 As individuals age, ulcer prevalence appears to increase exponentially.5 Anderson and associates noted that leg ulcers develop in 1% of the population over 70 years old; this incidence rises to 5% by age 90.6 In patients over age 65, 82% of the leg ulcers seen were secondary to venous insufficiency. These findings correlate well with earlier reports that indicated an 80% to 90% predominance of venous ulceration.7