RT Book, Section A1 Goodman, Catherine A1 Helgeson, Kevin SR Print(0) ID 1133951747 T1 Diabetes Mellitus, Type 1 T2 Exercise Prescription for Medical Conditions: Handbook for Physical Therapists YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780803617148 LK fadavispt.mhmedical.com/content.aspx?aid=1133951747 RD 2024/03/28 AB This condition is due to an autoimmune destruction of the insulin-secreting beta cells of the pancreas. This destruction can be rapid, resulting in this condition presenting in childhood or developing slowly with an initial presentation during early adulthood. The condition results in insufficient levels of insulin to transport glucose into cells, which leads to utilization of fats and proteins as sources of energy, causing severe weight loss and fatigue. Excessive metabolism of fats results in a state of ketoacidosis that can become life-threatening. Clients need ongoing assessment of their blood glucose levels to ensure tight control is maintained, with a proper balance of exogenous insulin, food intake, and exercise.1 Those who do not control their insulin levels will have limited endurance and develop severe fatigue from increased ketones in the blood stream. Children with this condition who do not have adequate control of their food intake and insulin levels may restrict their physical activities to prevent episodes of ketoacidosis and other complications. Long-term control of hyperglycemia is assessed by the percentage of glycated hemoglobin known as the A1C test.