TY - CHAP M1 - Book, Section TI - Venous Insufficiency and Ulceration A1 - McCulloch, Joseph M. A2 - McCulloch, Joseph M. A2 - Kloth, Luther C. PY - 2010 T2 - Wound Healing Evidence-Based Management, 4e AB - It has been suggested that approximately 90% of the estimated 600,000 leg ulcers seen annually in the United States are due to chronic venous disease or mixed arteriovenous insufficiency.1 In addition, 5% to 8% of the world's population is affected by venous disease, making this a costly problem from both an economic and quality-of-life perspective.2,3,4 As individuals age, ulcer prevalence appears to increase exponentially.5 Anderson and associates noted that leg ulcers develop in 1% of the population over 70 years old; this incidence rises to 5% by age 90.6 In patients over age 65, 82% of the leg ulcers seen were secondary to venous insufficiency. These findings correlate well with earlier reports that indicated an 80% to 90% predominance of venous ulceration.7 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - fadavispt.mhmedical.com/content.aspx?aid=1184831822 ER -