TY - CHAP M1 - Book, Section TI - Musculoskeletal Plasticity after SCI: A Conceptual Framework Based on Plasticity, Adaptation, and Outcome A1 - Shields, Richard K. A1 - Dudley-Javoroski, Shauna A2 - Field-Fote, Edelle C. PY - 2009 T2 - Spinal Cord Injury Rehabilitation AB - OBJECTIVESAfter reading this chapter, the reader will be able to:Enumerate the protein categories that underlie the plastic potential of skeletal muscleSummarize the major muscular adaptations to reduced use after SCIDiscuss the adaptations of paralyzed muscle to the reintroduction of loads via electrical stimulationDescribe how mechanotransduction and osteoclast/osteoblast activity underlie skeletal plasticitySummarize the adaptations of trabecular versus cortical bone to reduced use after SCI, along with consequences for bone strength and fracture riskDiscuss the concept of dose of loading in research protocols designed to preserve bone density after SCIDiscuss the subject-safety considerations of using electrical muscle stimulation to preserve musculoskeletal integrity after SCI (especially autonomic dysreflexia and fractures) SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - fadavispt.mhmedical.com/content.aspx?aid=1157251423 ER -