TY - CHAP M1 - Book, Section TI - Pharmacological Management of Parkinson Disease A1 - Ciccone, Charles D. PY - 2016 T2 - Pharmacology in Rehabilitation AB - Parkinson disease is a movement disorder characterized by resting tremor, bradykinesia, rigidity, and postural instability.1,2 In Parkinson disease, there is a slow, progressive degeneration of certain dopamine-secreting neurons in the basal ganglia.1,3 Several theories have been proposed to explain this spontaneous neuronal degeneration, including the possibility that the disease may be caused by a combination of genetic and environmental factors (see “Etiology of Parkinson Disease: Genetic and Environmental Factors").4–6 However, the precise initiating factor in Parkinson disease is still unknown. SN - PB - F. A. Davis Company CY - New York, NY Y2 - 2024/10/06 UR - fadavispt.mhmedical.com/content.aspx?aid=1135035245 ER -