TY  - CHAP
M1  - Book, Section
TI  - Topical Agents
A1  - Woo, Kevin Y.
A1  - Sibbald, R. Gary
A2  - McCulloch, Joseph M.
A2  - Kloth, Luther C.
Y1  - 2010
N1  - 
T2  - Wound Healing Evidence-Based Management, 4e
AB  - Topical  agents  can  be  selected  to  optimize  local  chronic  wound  care,  but  they  will  be  completely  ineffective  without  a  holistic  approach  to  patient  care.  Chronic  wounds  are  often  complex,  recalcitrant  to  healing,  and  may  persist  for  months  or  years  due  to  underlying  disease  processes  or  complications.  According  to  findings  from  control  populations  in  randomized  controlled  trials  (RCTs),  a  wound  that  is  not  30%  smaller  by  week  4  will  usually  not  heal  by  week  12.1,2  The  exact  mechanisms  that  contribute  to  poor  wound  healing  remain  elusive  but  likely  involve  an  interplay  of  systemic  and  local  factors.  The  wound  bed  preparation  (WBP)  model  was  proposed  by  Sibbald  et  al.3,4,5  to  systematically  manage  chronic  wounds  and  optimize  achievable  patient  outcomes.  (Fig.  13.1)  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - fadavispt.mhmedical.com/content.aspx?aid=1184831515
ER  -