TY - CHAP M1 - Book, Section TI - Multiple Sclerosis (MS) A1 - Goodman, Catherine A1 - Helgeson, Kevin Y1 - 2011 N1 - T2 - Exercise Prescription for Medical Conditions: Handbook for Physical Therapists AB - MS is characterized by the development of sclerotic plaques in the central nervous system, which results in blocked or slowed neural transmissions. MS has episodes of increased symptoms followed by periods of recovery. There are four subtypes, based on the pattern of progression of the disease. Initial symptoms are sensory changes, visual deficits, muscle weakness, and balance impairments. Diagnosis of MS is based on the clinical presentation of symptoms and the identification of lesions on magnetic resonance imaging (MRI) of the central nervous system. Clients with MS have periods of increased fatigue and weakness, resulting in limited daily activities. Inactivity is linked to decreased aerobic capacity, reduced muscle strength, increased fatigue, and reduced maximum gait velocity.1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - fadavispt.mhmedical.com/content.aspx?aid=1133952063 ER -