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Papillon-Lefèvre syndrome

(pa-pē-yon′ lĕ-fev′ĕr) [M. M. Papillon, P. Lefèvre, 20th-cent. Fr. dermatologists] A rare autosomal recessive disorder occurring between the first and fifth years of life marked by hyperkeratosis of the palms and soles, ectopic calcifications of the skull, severe periodontal disease, and early loss of teeth.


(pă-pil′ŏ-tōm″) [papilla + -tome] An instrument used to incise a papilla, e.g., the papilla of Vater.

Papio anubis

(pā′pē-ō″ ă-noo′bis) SEE: olive baboon.


(păp″ō-vă-vī′rŭs) [papilloma, + polyoma, + vacuolating agent + virus] Any of a group of viruses important in investigating viral carcinogenesis; including polyoma virus, simian virus 40 (SV 40), and papillomaviruses.


(păp′pŭs) [L.] The first growth of beard hair appearing on the cheeks and chin as fine, downy hair.

Pap smear, Pap test

(pap) Papanicolaou test.

anal P. s. A Pap smear in which cells are obtained from the anus in order to detect early changes that might presage the development of squamous cell carcinoma.


(păp′ūl) [L. papula, pimple] A small bump or pimple, typically larger than a grain of salt but smaller than a peppercorn, that rises above the surface of the neighboring skin. Papules may appear in numerous skin diseases, including prickly heat, psoriasis, xanthomatosis, eczema, and skin cancers. Their color may range from pale, to yellow, red, brown, or black. SEE: illus. papular (ū-lăr), adj.





dry p. Chancre.

moist p. Condyloma latum.

pearly penile p. An asymptomatic white papule with a pink, white, or pearly surface on the dorsum of the penis of blacks and uncircumcised men. No treatment is indicated, just reassurance.

piezogenic pedal p. A soft, painful, skin-colored papule present on the non–weight-bearing portion of the heel. It disappears when weight is taken off the foot and heel. This papule is caused by herniation of fat through connective tissue defects.

split p. Fissures at the corners of the mouth; seen in some cases of secondary syphilis.


[L. papula, pimple] Combining form indicating pimple, papule.


(păp″ū-lō-pŭs′tū-lăr) [″ + pustula, blister] Denoting the presence of both pustules and papules.


(pap″yŭ-lō′ sĭs) [papulo- +-sis] The presence of numerous and generalized papules.

malignant atrophic p. Degos disease.


(păp″ū-lō-skwā′ mŭs) [″ ...

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