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(grăn″ū-lō-sī-tō′sĭs) [″ ++ osis, condition] An abnormal increase in the number of granulocytes in the blood.


(gran″yŭ-lō′mă, gran″yŭ-lō′măt-ă) pl. granulomas, granulomata [granulo- + -oma] An inflammatory response that results when macrophages are unable to destroy foreign substances that have entered or invaded body tissues. Large numbers of macrophages are drawn to the affected area over 7 to 10 days, surround the target, and enclose it. They in turn are surrounded by polymorphonuclear leukocytes, other immune cells, and fibroblasts. Granulomas are common in many conditions, including leprosy, tuberculosis, cat scratch disease, some fungal infections, and foreign body reactions, e.g., reactions to sutures. granulomatous (gran″yŭ-lō′mă-tŭs), adj. SEE: giant cell; tuberculosis; Wegener granulomatosis.

g. annulare A circular rash with a raised red border, usually found on the hands, knuckles, or arms of young patients. The cause is unknown. The rash often lasts 1 or 2 years and then may disappear spontaneously. SEE: illus.




(On the back, near the left shoulder)


eosinophilic g. A form of xanthomatosis accompanied by eosinophilia and the formation of cysts on bone.

foreign body g. Chronic inflammation around foreign bodies such as sutures, talc, splinters, or gravel. SYN: foreign body.

g. inguinale A granulomatous ulcerative disease in which the initial lesion commonly appears in the genital area as a painless nodule.

 ETIOLOGY: This type of granuloma is caused by a short, gram-negative bacillus, Calymmatobacterium granulomatis (Donovan body).

 TREATMENT: Erythromycin, trimethoprim-sulfamethoxazole, or tetracyclines are used in treating this disease. Single-dose therapy with intramuscular ceftriaxone or oral ciprofloxacin may be effective.

pyogenic g. SEE: lobular capillary hemangioma.

pyrogenic g. SEE: lobular capillary hemangioma.

g. telangiectaticum A very vascular granuloma at any site, but esp. in the nasal mucosa or pharynx.

trichophytic g. Majocchi disease.


(gran″yŭ-lō″mă-tō′sĭs) [granuloma+ -osis] The development of multiple granulomas.

granulomatosis with polyangiitis

The preferred term for Wegener granulomatosis.


(gran″yŭ-lō-poy-ē′sĭs, gran″yŭ-lō-poy-ē′sēz″) pl. granulopoieses Granulocytopoiesis.


(gran″yŭ-lō′să) A layer of cells in the theca of the graafian follicle.


(grăn″ū-lō′sĭs) [″ + Gr. osis, condition] A mass of minute granules.

g. rubra nasi A disease of the skin of the nose, characterized by a moist erythematous patch on numerous macules. The disease is caused by an inflammatory infiltration about the nose, with ...

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