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cystic fibrosis

SEE: under fibrosis.


(sĭs″tĭ-kŏt′ō-mē) [″ + tome, incision] Incision of cystic bile duct. SYN: choledochotomy.


(sĭs′tĭ-form) [″ + L. forma, form] Having the form of a cyst.


(sĭs-tĭj′ĕr-ŭs) [″ + L. gerere, to bear] Containing cysts.


(sĭs′tēn) [Gr. kystis, bladder] C6H12N2S2O4; a sulfur-containing amino acid produced by the action of acids on proteins that contain this compound. It is an important source of sulfur in metabolism.


(sĭs″tĭ-nē′mē-ă) [cystine + Gr. haima, blood] The presence of cystine in the blood.

cystine storage disease

An inherited disease of cystine metabolism resulting in abnormal deposition of cystine in body tissues. The cause is disordered proximal renal tubular function. Clinically, the child fails to grow and develops rickets, corneal opacities, and acidosis.


(sĭs′tĭ-nō′sĭs) [″ + Gr. osis, condition] A rare, autosomal recessive disorder, one of the lysosomal storage diseases, that results in the deposition of cystine crystals in body tissues. Affected children develop growth failure, rickets, renal tubular acidosis, hypothyroidism, and kidney failure, often followed by lung disease, sexual dysfunction, and neurological disorders. SEE: cystine storage disease.


(sĭs″tĭ-nū′rē-ă) [″ + ouron, urine] 1. The presence of cystine in the urine. 2. A hereditary metabolic disorder characterized by excretion of large amounts of cystine, lysine, arginine, and ornithine in the urine. It results in the development of recurrent urinary calculi.


(sis-tīt′ĭs) [cyst- + -itis] Inflammation of the bladder, usually the result of a urinary tract infection. Associated organs (kidney, prostate, urethra) may be involved. The condition may be acute or chronic. Females are affected 10 times more than males. Adult males and children may develop lower urinary tract infections from anatomic or physiologic abnormalities such as prostatic hypertrophy (adult men) or anomalies of the ureterovesicular junction. The infection usually is ascending, caused by a gram-negative enteric bacterium, e.g., Escherichia coli, Klebsiella, Proteus, Enterobacter, Pseudomonas, or Serratia, and occasionally by gram-positives (Staphylococcus saprophyticus or enterococci). When an indwelling catheter is present or the patient has a neurogenic bladder, multiple pathogens may be responsible. SEE: Nursing Diagnoses Appendix.

 SYMPTOMS: Cystitis is marked by urinary urgency, frequency, and pain. Bladder spasms and perineal aching or fullness are also reported. Most patients do not have a fever.

 TREATMENT: Antibiotics are useful in treating the infection, but more definitive therapy is required if the basic cause is ...

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