One of a group of proteins on the surface of lymphocytes that enhance immune recognition. Immune cells that express the CD4 molecule are also known as helper T cells; they work with cells that express major histocompatibility complex (MHC) class II molecules to recognize antigens and stimulate cell-mediated and humoral immune responses. The human immunodeficiency virus (HIV) uses the CD4 receptor to infect T lymphocytes, macrophages, and other immunologic cells. SEE: AIDS; cluster of differentiation.
An immunoglobulin embedded within a cell membrane, expressed on the surface of mature T lymphocytes and thymocytes. SEE: cluster of differentiation.
An antigenic protein found only on the surface of B lymphocytes. It can be used to identify and separate those cells from others and can be exploited as a target for monoclonal antibody therapy. Monoclonal antibodies that block CD20 include rituximab and ofatumumab.
The interleukin-2 receptor.
A membrane-bound cell surface antigen present on and identifying T cells, monocytes, and macrophages. It is found principally on endothelial cells and blood-forming stem cells, and regulates cell-to-cell adhesion.
A cell surface glycoprotein heavily expressed by several blood and lymphatic cancers. SEE: cluster of differentiation.
A cell surface antigen expressed on many natural killer cells. SEE: cluster of differentiation.
A glycoprotein expressed on monocytes and tissue macrophages. SEE: cluster of differentiation.
A cell surface glycoprotein used in immunohistochemistry to identify monocytes and macrophages. SEE: cluster of differentiation.
Canadian Dental Association; Certified Dental Assistant.
Centers for Disease Control and Prevention.
Certified Diabetes Educator.
Center for Drug Evaluation and Research.
congenital diaphragmatic hernia of the neonate; congenital dislocation of the hip; congenital dysplasia of the hip.
Certified Dialysis Nurse.
Certified driver rehabilitation specialist.
A gut protein used clinically in immunocytochemistry to identify adenocarcinomas of the colon and other tissues and tumors of intestinal origin.
Symbol for the element cerium.