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(hĕp″ă-tō-lĭ-thī′ă-sĭs) [″ + ″ + ″ -iasis, disease condition] A condition characterized by stones in the intrahepatic ducts.


(hĕp″ă-tŏl′ō-jĭst) [″ + logos, word, reason] A specialist in diseases of the liver.


(hĕp″ă-tŏl′ō-jē) [″ + logos, word, reason] The study of the liver.


(hĕp″ă-tō′mă) [″ + oma, tumor] Any liver tumor, benign or malignant. The term is usually used to describe a hepatocellular carcinoma.


(hep″ăt-ō-meg′ă-lē) [hepato- + -megaly] Enlargement of the liver, e.g., in alcoholic hepatitis, passive congestion of the liver, or liver cancer.


(hep″ăt-ō-port″ō-ent″ ĕ-ros′tŏ-mē) Hepatic portoenterostomy.

hepatopulmonary syndrome

(hĕp″ă-tō-pŭl′mō-năr″ē) [″ + L. pulmo, lung] A combination of liver disease, decreased arterial oxygen concentration, and dilatation of the blood vessels of the lung. Clinically the patient may have signs and symptoms of liver disease, including gastrointestinal bleeding, esophageal varices, ascites, palmar erythema, and splenomegaly. Pulmonary signs include clubbing of the fingers, cyanosis, dyspnea, and decreased arterial oxygen concentration while in an upright position (orthodeoxia).


(hĕp″ă-tō-rē′năl) [″ + L. renalis, kidney] Pert. to the liver and kidneys.

hepatorenal syndrome

(hep″ăt-ō-pul′mŏ-ner″ē, -pŭl′) ABBR: HRS. Renal failure resulting from abnormal kidney perfusion in patients with cirrhosis and ascites. Patients with HRS are typically critically ill and have a very poor prognosis. Liver transplantation or portosystemic shunts are occasionally effective treatments.


(hĕp-ă-tor′ă-fē) [″ + rhaphe, seam, ridge] The suturing of a wound of the liver.


(hĕp″ă-tō-splē″nō-mĕg′ă-lē) [″ + ″ + ″] Enlargement of the liver and spleen.


(hĕp″ă-tŏt′ō-mē) [″ + tome, incision] An incision into the liver.


(hĕp″ă-tō-tŏks′ĭk) Toxic to the liver.


(hĕp″ă-tō-tŏk′sĭn) A cytotoxin specific for liver cells.


(hep sĭd-ĭn) A protein secreted by the liver that acts as a regulatory hormone that controls the amount of iron in the body. Elevated levels of hepcidin in the blood prevent iron from being taken up by red blood cells. Hepcidin levels rise in many chronic illnesses and infections, causing the anemia of chronic disease. Proteins or hormones (like testosterone) that block the action of hepcidin result, by contrast, in iron overload diseases and erythrocytosis.


A genus of single-stranded RNA virus. Hepatitis E virus is the sole pathogenic member of the genus. SEE: hepatitis E.

hept-, hepta-

[Gr. hepta, seven] Prefixes meaning seven.



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