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(hē″mō-dī-al′ĭ-sĭs, ′ĭ-sēz″) pl. hemodialyses [hemo- + dialysis] The clearing of urea, metabolic waste products, toxins, and excess fluid from the blood by use of an artificial kidney. This procedure is used to treat end-stage renal failure, transient renal failure, and some cases of poisoning or drug overdose. In the U.S., more than 345,000 patients undergo hemodialysis regularly for end-stage renal disease. The primary use of hemodialysis is to manage renal failure, a disorder in which fluids, acids, electrolytes, and many drugs are ineffectively eliminated in the urine. Hyperkalemia, uremia, fluid overload, acidosis, and uremic pericarditis are other indications for hemodialysis. SEE: table; hemoperfusion; Nursing Diagnoses Appendix.
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Hemodialysis separates solutes by differential diffusion through a cellophane membrane placed between the blood and the dialysate solution, and involves the following: 1) establishing access to the circulation, e.g., via an arteriovenous fistula, cannula, or via a synthetic or bovine graft or temporary catheter; 2) anticoagulating the patient's blood to prevent extracorporeal clotting; 3) pumping the blood to a dialysis membrane; 4) adjusting the diffusion of solutes from the blood into a buffered dialysate solution; 5) returning the cleansed and buffered blood to the patient.
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Adequacy of hemodialysis is determined by the amount of fluid and solute, esp. urea, removed from the body. Typically, hemodialysis lasts about 3 or 4 hr per treatment and is repeated several times a week.
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Even with regular hemodialysis sessions, patients with end-stage renal disease have high mortality rates. In the U.S., about 25% of all patients receiving hemodialysis die each year, usually because of heart disease, stroke, or pre-existing diabetes mellitus. SYN: renal dialysis. SEE: dialysis; hemofiltration; uremia.
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Hemodialysis has many potential complications, including hypotension, infection of the site of access, sepsis, air embolism, hypersensitivity reactions, dialysis disequilibrium, muscle cramping, anemia, and bleeding.
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PATIENT CARE: Preprocedure: If this is the patient's first hemodialysis session, the purpose of the treatment and expected results ...