RT Book, Section A1 Ovington, Liza G. A2 McCulloch, Joseph M. A2 Kloth, Luther C. SR Print(0) ID 1184831448 T1 Dressings and Skin Substitutes T2 Wound Healing Evidence-Based Management, 4e YR 2010 FD 2010 PB McGraw-Hill Education PP New York, NY SN 9780803619043 LK fadavispt.mhmedical.com/content.aspx?aid=1184831448 RD 2024/04/20 AB This chapter provides an overview of wound dressings developed for the management of chronic wounds as well as a discussion of products commonly known as skin substitutes. At first glance, it may seem incongruous to cover wound dressings and skin substitutes in one chapter; however, if one seeks to generally define these two classes of products, the similarity becomes apparent. Wound dressings are a predominantly synthetic and heterogeneous group of medical devices that aid in the topical management of a wide variety of wound types and conditions and that vary greatly in their materials of composition as well as their purported mechanisms of action. Skin substitutes are a predominantly biological and heterogeneous group of substances that aid in the temporary or permanent closure of a wide variety of wound types and that may also vary greatly in their materials of composition and purported mechanisms of action. The differences between the two categories are specifically their materials of composition and proposed mechanisms of action. One might actually view skin substitutes as a natural progression of dressing technology. In clinical practice, these two categories of products are often used simultaneously and or sequentially in the course of wound management.