RT Book, Section
A1 Goodman, Catherine
A1 Helgeson, Kevin
SR Print(0)
ID 1133952304
T1 Sickle Cell Disease
T2 Exercise Prescription for Medical Conditions: Handbook for Physical Therapists
YR 2011
FD 2011
PB McGraw-Hill Education
PP New York, NY
SN 9780803617148
LK fadavispt.mhmedical.com/content.aspx?aid=1133952304
RD 2024/04/19
AB This  disease  is  a  group  of  inherited  disorders  that  produces  an  abnormal  type  of  hemoglobin  that  causes  red  blood  cells  to  take  on  a  sickle  shape  during  deoxygenation.  Sickling  of  red  blood  cells  leads  to  lysis  that  results  in  anemia  and  vaso-occlusion.  Sickled  red  blood  cells  form  clots  in  organs,  joints,  and  bones  that  produce  painful  episodes  or  crises.  Sickle  cell  episodes  can  lead  to  damage  to  the  spleen,  with  anemia  leading  to  infections  and  systemic  complications.  Clients  may  have  frequent  crises  that  require  ongoing  medical  management  and  complications.  Infants  are  routinely  screened  for  this  disease.  Clients  are  counseled  to  control  their  activities  and  stressors  that  may  trigger  a  crises  episode.  Daily  activities  are  difficult  to  complete  if  a  client  with  sickle  cell  disease  has  chronic  anemia.1,2