RT Book, Section A1 Goodman, Catherine A1 Helgeson, Kevin SR Print(0) ID 1133952261 T1 Rhabdomyolysis T2 Exercise Prescription for Medical Conditions: Handbook for Physical Therapists YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780803617148 LK fadavispt.mhmedical.com/content.aspx?aid=1133952261 RD 2024/04/24 AB This condition is secondary to the breakdown of skeletal muscle fibers and seepage of the contents into the bloodstream. There are numerous causes, including traumatic crush, electrical injuries, ingestion of toxic substances, and exertional rhabdomyolysis, which occurs in endurance athletes and military personnel. A side effect of taking cholesterol-lowering statins can be the development of myopathies, which can progress to rhabdomyolysis.1,2 The resulting complications include hyperkalemia, cardiac arrhythmias, and acute renal failure, which may lead to death. Early recognition of rhabdomyolysis will prevent the long-term complications from the loss of skeletal muscle and decreased renal and liver function.3,4 Individuals who develop rhabdomyolysis will be counseled to avoid strenuous activities for a period of weeks to allow for return of kidney, liver, and cardiac function.5 Individuals who have suffered heat overexertion may have long-term intolerance to heat/humidity conditions and decreased blood lactase thresholds.4