RT Book, Section A1 Goodman, Catherine A1 Helgeson, Kevin SR Print(0) ID 1133951866 T1 Hemophilia T2 Exercise Prescription for Medical Conditions: Handbook for Physical Therapists YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780803617148 LK fadavispt.mhmedical.com/content.aspx?aid=1133951866 RD 2024/04/25 AB Hemophilia is a bleeding disorder caused by abnormal plasma-clotting proteins. Clients with hemophilia have prolonged bleeding times and the risk of internal hemorrhaging into joints and muscles. This disorder is classified by the client's percentage of clotting factors: mild is 5% to 50%; moderate is 1% to 5%; severe is <1%. Patients with moderate and severe hemophilia will need factor replacement therapy to control and prevent excessive bleeding. Individuals with hemophilia may develop limited endurance from a combination of factors that include repeated joint bleeds, pain and limited joint mobility, muscle atrophy, and fear of injury. Limited endurance is associated with decreased muscle strength, joint stability, and proprioception.1,2