RT Book, Section A1 Goodman, Catherine A1 Helgeson, Kevin SR Print(0) ID 1133951322 T1 Bone Marrow Transplant T2 Exercise Prescription for Medical Conditions: Handbook for Physical Therapists YR 2011 FD 2011 PB McGraw-Hill Education PP New York, NY SN 9780803617148 LK fadavispt.mhmedical.com/content.aspx?aid=1133951322 RD 2024/04/19 AB A transplant of hematopoietic stem cells from bone marrow, peripheral blood, or umbilical cord blood into a client's bone marrow is a life-saving procedure. Clients typically have a type of cancer that requires chemotherapy or radiation that destroys the bone marrow in order to stop the progression of their disease. The bone marrow is repopulated with healthy stem cells that can differentiate into mature blood cells. The hematopoietic stem cells can be from an allogeneic donor, usually a close relative, or from the person's own (autologous) blood. Clients undergoing this procedure may have numerous complications that will require hospitalization and involvement of many health-care providers. This procedure places the client under a great amount of physical, emotional, and psychosocial stress.1 Clients are deconditioned due to significant declines in function and independence resulting from treatment of their disease process and the transplant procedure.2 Exercise interventions after hematopoietic stem cell transplantation have many potential benefits for the client.1