RT Book, Section
A1 Roy, Serge H.
A1 Wolf, Steven L.
A1 Scalzitti, David A.
SR Print(0)
ID 1133438252
T1 Physical Agents
T2 The Rehabilitation Specialist's Handbook, 4e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 9780803639065
LK fadavispt.mhmedical.com/content.aspx?aid=1133438252
RD 2024/04/23
AB Table  Graphic  Jump  LocationTABLE  18.1Interactions  Between  Drugs  and  Commonly  Used  Physical  ModalitiesView  Table||Download  (.pdf)TABLE  18.1Interactions  Between  Drugs  and  Commonly  Used  Physical  ModalitiesModalityDesired  Therapeutic  EffectDrugs  With  Complementary/  Synergistic  EffectsDrugs  With  Antagonistic  EffectsOther  Drug–Modality  InteractionsCryotherapyCold/ice  packs,  ice  massage,  cold  baths,  vapocoolant  spraysDecreased  pain,  edema,  and  inflammationMuscle  relaxation  and  decreased  spasticityAnti-inflammatory  steroids  (glucocorticoids);  non-steroidal  anti-inflammatory  analgesics  (aspirin  and  similar  NSAIDs)Skeletal  muscle  relaxantsPeripheral  vasodilators  may  exacerbate  acute  local  edema.Nonselective  cholinergic  agonists  may  stimulate  the  neuromuscular  junction.Some  forms  of  cryotherapy  may  produce  local  vasoconstriction  that  temporarily  impedes  diffusion  of  drugs  to  the  site  of  inflammation.ThermotherapyHot  packsParaffinInfraredFluidotherapyDiathermyUltrasoundDecreased  muscle/joint  pain  and  stiffnessDecreased  muscle  spasmsIncreased  blood  flow  to  improve  tissue  healingNSAIDs;  opioid  analgesics;  local  anestheticsSkeletal  muscle  relaxantsPeripheral  vasodilatorsNonselective  cholinergic  agonists  may  stimulate  the  neuromuscular  junction.Systemic  vasoconstric  tors  (e.g.,  α-1  agonists)  may  decrease  perfusion  of  peripheral  tissues.  Systemic  HeatLarge  whirlpool  Hubbard  tankDecreased  muscle/  joint  stiffness  in  large  areas  of  the  bodyOpioid  and  nonopioid  analgesics;  skeletal  muscle  relaxants  Severe  hypotension  may  occur  if  systemic  hot  whirlpool  is  administered  to  patients  taking  peripheral  vasodilators  and  some  antihypertensive  drugs  (e.g.,  α-1  antagonists,  nitrates,  direct-acting  vasodilators,  calcium  channel  blockers).Ultraviolet  radiationIncreased  wound  healingManagement  of  skin  disorders  (acne,  rashes)Various  systemic  and  topical  antibioticsSystemic  and  topical  antibiotics  and  anti-inflammatory  steroids  (glucocorticoids)Many  drugs  may  cause  hypersensitivity  reactions  that  result  in  skin  rashes,  itching.Antibacterial  drugs  generally  increase  cutaneous  sensitivity  to  ultraviolet  light  (i.e.,  photosensitivity).Photosensitivity  with  antibacterial  drugs.Transcutaneous  electrical  nerve  stimulation  (TENS)Decreased  painOpioid  and  nonopioid  analgesicsOpioid  antagonists  (naloxone).  Functional  electrical  stimulation  (FES)Increased  skeletal  muscle  strength  and  enduranceDecreased  spasticity  and  muscle  spasmsSkeletal  muscle  relaxantsSkeletal  muscle  relaxants.Nonselective  cholinergic  agonists  may  stimulate  the  neuromuscular  junction.  From  Ciccone,  CD:  Pharmacology  in  Rehabilitation,  ed.  3.  FA  Davis,  Philadelphia,  1996,  inside  front  cover,  with  permission.