TY  - CHAP
M1  - Book, Section
TI  - Constraint-Induced Movement Therapy
A1  - Morris, David M.
A1  - Taub, Edward
A2  - O’Sullivan, Susan B.
A2  - Schmitz, Thomas J.
PY  - 2016
T2  - Improving Functional Outcomes in Physical Rehabilitation, 2e
AB  - Constraint-induced  movement  therapy,  or  CI  therapy,  involves  a  variety  of  intervention  components  used  to  promote  increased  use  of  a  more-impaired  extremity  in  the  clinic  setting,  the  research  laboratory,  and,  most  importantly,  in  the  home  setting.1,2,3,4,5,6,7,8,9,10,11,12,13,14,15  The  CI  therapy  protocol  has  its  origins  in  basic  animal  research  that  led  Taub  to  propose  a  behavioral  mechanism  that  can  interfere  with  recovery  from  a  neurological  insult—learned  nonuse.11,16,17  A  linked  but  separate  mechanism,  use-dependent  brain  plasticity,  has  also  been  proposed  as  partially  responsible  for  producing  positive  outcomes  from  CI  therapy.18,19,20,21,22,23,24,25  Substantial  evidence  has  accumulated  to  support  the  efficacy  of  CI  therapy  for  hemiparesis  after  chronic  stroke  (i.e.,  greater  than  1-year  post  injury).4,26  Evidence  for  efficacy  comes  from  several  studies:  an  initial  small,  randomized  controlled  trial  (RCT)  of  CI  therapy  in  patients  with  upper  extremity  (UE)  hemiparesis  secondary  to  chronic  stroke,1  a  larger  placebo  controlled  trial  in  patients  of  the  same  chronicity  and  level  of  impairment,27  and  a  number  of  other  studies.2,3,4,5,6,7,8,9  There  has  also  been  a  large  multisite  randomized  clinical  trial  in  patients  with  UE  hemiparesis  in  the  subacute  phase  of  recovery  (i.e.,  3–9  months  poststroke).28,29,30  Positive  findings  regarding  CI  therapy  after  chronic  stroke  are  also  published  in  several  studies  from  other  laboratories  employing  between-group  and  within-subjects  control  procedures  and  numerous  case  studies.31,32,33,34,35  Altogether,  several  hundred  studies  on  the  clinical  effects  of  CI  therapy  have  been  published,  almost  all  with  positive  results.  Moreover,  the  most  recent  poststroke  clinical  care  guidelines,  developed  by  a  working  group  organized  by  the  Veteran's  Administration  and  Department  of  Defense,  describe  CI  therapy  as  an  intervention  that  has  evidence  of  benefit  for  survivors  of  stroke  with  mild-to-moderate  UE  hemiparesis.35  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - fadavispt.mhmedical.com/content.aspx?aid=1134945210
ER  -