TY - CHAP M1 - Book, Section TI - Hemophilia A1 - Goodman, Catherine A1 - Helgeson, Kevin Y1 - 2011 N1 - T2 - Exercise Prescription for Medical Conditions: Handbook for Physical Therapists AB - Hemophilia is a bleeding disorder caused by abnormal plasma-clotting proteins. Clients with hemophilia have prolonged bleeding times and the risk of internal hemorrhaging into joints and muscles. This disorder is classified by the client's percentage of clotting factors: mild is 5% to 50%; moderate is 1% to 5%; severe is <1%. Patients with moderate and severe hemophilia will need factor replacement therapy to control and prevent excessive bleeding. Individuals with hemophilia may develop limited endurance from a combination of factors that include repeated joint bleeds, pain and limited joint mobility, muscle atrophy, and fear of injury. Limited endurance is associated with decreased muscle strength, joint stability, and proprioception.1,2 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/20 UR - fadavispt.mhmedical.com/content.aspx?aid=1133951866 ER -