TY - CHAP M1 - Book, Section TI - Cushing Syndrome A1 - Goodman, Catherine A1 - Helgeson, Kevin Y1 - 2011 N1 - T2 - Exercise Prescription for Medical Conditions: Handbook for Physical Therapists AB - This condition results from excessive levels of cortisol, usually due to adrenocortical tumors or high doses of hydrocortisone or cortisol-derivative drugs. Excessive cortisol results in numerous physiological responses, which include muscle weakness, bone demineralization, weakening of elastic tissues, hyperglycemia, and obesity. Removal of adrenocortical tumors will reverse this syndrome, but patients who rely on hydrocortisone to control their inflammatory disease processes may be unable to reverse this syndrome completely. Removal of the tumor may affect other pituitary hormones, especially growth hormone.1 The loss of muscle tissues will greatly affect tolerance for daily activities and lead to deconditioning with impaired endurance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/24 UR - fadavispt.mhmedical.com/content.aspx?aid=1133951679 ER -