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inoculate

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(in-ok′yŭ-lāt″) [L. inoculare, to graft, implant] To inject an antigen, antiserum, or antitoxin into an individual to produce immunity to a specific disease. SEE: vaccine.

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inoculation

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(ĭn-ŏk″ū-lā′shŭn) 1. The injection or introduction of an antigen or microbe into a person, animal, or organ or into a solution, growth medium, or other laboratory apparatus. 2. Vaccination. This can be accomplished parenterally (through the skin), orally, or intranasally; by using an aerosol mist; or by scarification of the skin.

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animal i. The injection of serums, microorganisms, or viral organisms into laboratory animals for the purpose of immunizing them or of investigating the effects of the inoculated material on them.

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inoculum

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(ĭn-ŏk′ū-lŭm) [L.] A substance introduced by inoculation.

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inoculum effect

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In pharmacology, an increase in drug resistance that occurs with a larger burden of infecting organisms.

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inoperable

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(ĭn-ŏp′ĕr-ă-bl) [L. in-, not, + operari, to work] Unsuitable for surgery. In the case of a tumor, the disease may have spread so extensively as to make surgery ineffective, or the patient's general condition may be so poor that surgery could result in the patient's death.

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inorganic

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(ĭn″or-găn′ĭk) [L. in-, not, + Gr. organon, an organ] 1. In chemistry, occurring in nature independently of living things; sometimes considered to indicate chemical compounds that do not contain carbon. 2. Not pert. to living organisms.

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inosculate

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(ĭn-ŏs′kū-lāt″) [L. in, in, + osculum, little mouth] Anastomose.

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inosculation

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(ĭn-ŏs″kū-lā′shŭn) Anastomosis.

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inose

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(ĭn′ōs) Inositol.

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inosemia

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(ĭn-ō-sē′mē-ă) [Gr. inos, fiber, + haima, blood] 1. An excessive amount of fibrin in the blood. 2. The presence of inositol in the blood.

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inosite

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(ĭn′ō-sīt) Inositol.

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inositol

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(i-nō′sĭ-tol″) Hexahydroxycyclohexane, C6H6(OH)6; a sugar-like crystalline substance found in the liver, kidney, skeletal muscle, and heart muscle, as well as in the leaves and seeds of most plants. It is part of the vitamin B complex. Deficiency of inositol in experimental animals results in hair loss, eye defects, and growth retardation. Its significance in human nutrition has not been established. SYN: inose; inosite.

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inositol-1,4,5-triphosphate

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(i-nō′sĭ-tol″) ABBR: IP3. An intracellular second messenger molecule that stimulates the endoplasmic reticulum of the cell to release calcium.

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inosituria

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(ĭn″ō-sī-tū′rē-ă) [inositol + Gr. ouron, urine] Inosuria.

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inosuria

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(ĭn-ō-sū′rē-ă) [inositol + Gr. ouron, urine] 1. Inositol in the urine. SYN: inosituria. 2....

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