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sclero-, sclera-, scler-

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[Gr. sklēros, hard] Prefixes meaning hard.

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sclerocornea

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(sklĕ″rō-kor′nē-ă) [″ + L.corneus, horny] The sclera and cornea together considered as one coat.

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sclerodactylia

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(sklĕr″ō-dăk-tĭl′ē-ă) [″ + daktylos, a finger] Induration of the skin of the fingers and toes. SYN: acroscleroderma.

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scleroderma

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(sklĕr″ŏ-dĕr′mă) [sclero- + derma] A chronic manifestation of progressive systemic sclerosis in which the skin is taut, firm, and edematous, limiting movement. SYN: dermatosclerosis. SEE: progressive systemic sclerosis. sclerodermatous, adj.

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circumscribed s. Localized patches of linear sclerosis of the skin. There is no systemic involvement, and the course of the disease is usually benign.

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s. neonatorum Sclerema neonatorum.

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sclerogenic

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(sklĕ″rō-jĕn′ĭk) [″ + gennan, to produce] Causing sclerosis or hardening of tissue. SYN: sclerogenous.

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sclerokeratitis

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(sklĕr″ō-kĕr-ă-tī′tĭs) [″ + keras, horn, + itis, inflammation] Cellular infiltration with inflammation of the sclera and cornea. SYN: sclerokeratosis.

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scleroma

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(sklĕ-rō′mă) [″ + oma, tumor] An indurated, circumscribed area of granulation tissue in the mucous membrane or skin. SEE: sclerosis.

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scleromalacia

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(sklĕ″rō-mā-lā′sē-ă) [Gr. skleros, hard, + malakia, softening] A softening of the sclera.

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s. perforans A severe form of necrotizing anterior scleritis usually found in patients with an underlying systemic inflammatory illness, e.g., rheumatoid arthritis.

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scleromyxedema

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(sklĕr″ō-mĭk″sē-dē′mă) [″ + myxa, mucus, + oidema, swelling] A systemic form of papular mucinosis (also known as lichen myxedematosus), in which a scleroderma-like rash is accompanied by lesions of visceral organs and often paraproteinemia.

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scleroplasty

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(sklĕ′rō-plăs″tē) [″ + plassein, to form] Plastic surgery of the sclera.

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scleroprotein

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(sklĕ″rō-prō′tē-ĭn) [″ + protos, first] A group of proteins noted for their insolubility in most chemicals; found in skeletal tissue, cartilage, hair, and nails and in animal claws and horns.

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sclerosant

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(sklĕ-rō′sănt) [sclero-] Something that produces sclerosis. SYN: sclerosing solution.

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sclerose

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(sklĕ-rōs′) [Gr. skleros, hard] To become hardened. sclerosing, scle-rosed, adj.

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sclerosis

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(sklĕ-rō′sĭs) [Gr. sklērōsis, hardening] A hardening or induration of an organ or tissue, esp. one due to excessive growth of fibrous tissue. SEE: arteriosclerosis; cerebrosclerosis. sclerotic (-rot ik), adj.

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amyotrophic lateral s. ABBR: ALS. Motor neuron disease.

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annular s. Sclerosis in which a hardened substance forms a band about the spinal cord.

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arterial s. Arteriosclerosis.

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arteriolar s. Sclerosis of the arterioles.

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diffuse s....

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